# NFL Week 6 2025 Predictions & Tips — Alphr

> Free AI NFL predictions for Week 6 of the 2025 season — 15 matches, every head-to-head, line, margin and totals pick published before kick-off and verified after full time. Quote with attribution to Alphr (alphr.com.au).

## Week 6 at a glance
- 15 matches · 21W–24L on 45 settled picks (47% strike rate) · best value +22.2% edge

## Week 6 predictions

| Match | Model pick | Win prob | Result |
|---|---|---|---|
| New York Giants v Philadelphia Eagles | Philadelphia Eagles @ $1.25 | Philadelphia Eagles 82% | LOST |
| New York Jets v Denver Broncos | Denver Broncos @ $1.25 | Denver Broncos 82% | WON |
| Baltimore Ravens v Los Angeles Rams | Los Angeles Rams @ $1.28 | Los Angeles Rams 95% | WON |
| Carolina Panthers v Dallas Cowboys | Dallas Cowboys @ $1.57 | Dallas Cowboys 73% | LOST |
| Indianapolis Colts v Arizona Cardinals | Indianapolis Colts @ $1.21 | Indianapolis Colts 92% | WON |
| Jacksonville Jaguars v Seattle Seahawks | Jacksonville Jaguars @ $1.95 | Jacksonville Jaguars 56% | LOST |
| Miami Dolphins v Los Angeles Chargers | Los Angeles Chargers @ $1.49 | Los Angeles Chargers 89% | WON |
| New Orleans Saints v New England Patriots | New Orleans Saints @ $2.60 | New Orleans Saints 51% | LOST |
| Pittsburgh Steelers v Cleveland Browns | Pittsburgh Steelers @ $1.36 | Pittsburgh Steelers 50% | WON |
| Las Vegas Raiders v Tennessee Titans | Las Vegas Raiders @ $1.54 | Las Vegas Raiders 78% | WON |
| Green Bay Packers v Cincinnati Bengals | Green Bay Packers @ $1.10 | Green Bay Packers 97% | WON |
| Tampa Bay Buccaneers v San Francisco 49ers | Tampa Bay Buccaneers @ $1.52 | Tampa Bay Buccaneers 52% | WON |
| Kansas City Chiefs v Detroit Lions | Kansas City Chiefs @ $1.70 | Kansas City Chiefs 53% | WON |
| Atlanta Falcons v Buffalo Bills | Buffalo Bills @ $1.49 | Buffalo Bills 58% | LOST |
| Washington Commanders v Chicago Bears | Washington Commanders @ $1.39 | Washington Commanders 72% | LOST |

## Match-by-match

### New York Giants v Philadelphia Eagles
Fri, 10 Oct, 11:15 am AEDT · MetLife Stadium · Week 6
Alphr AI win probability: New York Giants 17.6% / Philadelphia Eagles 82.4%
- **Head to Head:** Philadelphia Eagles to win @ $1.25 (edge +2.6%) — model probability 82.4% — result: LOST
- **Line / Spread:** Philadelphia Eagles -7 @ $1.91 (edge +0.0%) — result: LOST
- **Total (Over/Under):** Over 40.5 @ $1.91 (edge +0.0%) — result: WON
- Predicted margin: Philadelphia Eagles by 21 · Predicted total: 44
Full breakdown: https://alphr.com.au/nfl/match/2025-r6-new-york-giants-v-philadelphia-eagles

### New York Jets v Denver Broncos
Mon, 13 Oct, 12:30 am AEDT · MetLife Stadium · Week 6
Alphr AI win probability: New York Jets 18.4% / Denver Broncos 81.6%
- **Head to Head:** Denver Broncos to win @ $1.25 (edge +1.8%) — model probability 81.6% — result: WON
- **Line / Spread:** Denver Broncos -7.5 @ $1.91 (edge +0.0%) — result: LOST
- **Total (Over/Under):** Over 43.5 @ $1.91 (edge +0.0%) — result: LOST
- Predicted margin: Denver Broncos by 13 · Predicted total: 46
Full breakdown: https://alphr.com.au/nfl/match/2025-r6-new-york-jets-v-denver-broncos

### Baltimore Ravens v Los Angeles Rams
Mon, 13 Oct, 04:00 am AEDT · M&T Bank Stadium · Week 6
Alphr AI win probability: Baltimore Ravens 4.6% / Los Angeles Rams 95.4%
- **Head to Head:** Los Angeles Rams to win @ $1.28 (edge +17.4%) — model probability 95.4% — result: WON
- **Line / Spread:** Baltimore Ravens +7 @ $1.91 (edge +0.0%) — result: LOST
- **Total (Over/Under):** Over 43.5 @ $1.91 (edge +0.0%) — result: LOST
- Predicted margin: Los Angeles Rams by 12 · Predicted total: 45
Full breakdown: https://alphr.com.au/nfl/match/2025-r6-baltimore-ravens-v-los-angeles-rams

### Carolina Panthers v Dallas Cowboys
Mon, 13 Oct, 04:00 am AEDT · Bank of America Stadium · Week 6
Alphr AI win probability: Carolina Panthers 27.4% / Dallas Cowboys 72.6%
- **Head to Head:** Dallas Cowboys to win @ $1.57 (edge +9.0%) — model probability 72.6% — result: LOST
- **Line / Spread:** Dallas Cowboys -3 @ $1.91 (edge +0.0%) — result: LOST
- **Total (Over/Under):** Over 47.5 @ $1.91 (edge +0.0%) — result: WON
- Predicted margin: Dallas Cowboys by 4 · Predicted total: 48
Full breakdown: https://alphr.com.au/nfl/match/2025-r6-carolina-panthers-v-dallas-cowboys

### Indianapolis Colts v Arizona Cardinals
Mon, 13 Oct, 04:00 am AEDT · Lucas Oil Stadium · Week 6
Alphr AI win probability: Indianapolis Colts 91.8% / Arizona Cardinals 8.2%
- **Head to Head:** Indianapolis Colts to win @ $1.21 (edge +9.3%) — model probability 91.8% — result: WON
- **Line / Spread:** Arizona Cardinals +8.5 @ $1.91 (edge +0.0%) — result: WON
- **Total (Over/Under):** Over 46.5 @ $1.91 (edge +0.0%) — result: WON
- Predicted margin: Indianapolis Colts by 5 · Predicted total: 48
Full breakdown: https://alphr.com.au/nfl/match/2025-r6-indianapolis-colts-v-arizona-cardinals

### Jacksonville Jaguars v Seattle Seahawks
Mon, 13 Oct, 04:00 am AEDT · TIAA Bank Stadium · Week 6
Alphr AI win probability: Jacksonville Jaguars 56.3% / Seattle Seahawks 43.7%
- **Head to Head:** Jacksonville Jaguars to win @ $1.95 (edge +5.1%) — model probability 56.3% — result: LOST
- **Line / Spread:** Jacksonville Jaguars +1.5 @ $1.91 (edge +0.0%) — result: LOST
- **Total (Over/Under):** Under 47.5 @ $1.91 (edge +0.0%) — result: WON
- Predicted margin: Jacksonville Jaguars by 3 · Predicted total: 47
Full breakdown: https://alphr.com.au/nfl/match/2025-r6-jacksonville-jaguars-v-seattle-seahawks

### Miami Dolphins v Los Angeles Chargers
Mon, 13 Oct, 04:00 am AEDT · Hard Rock Stadium · Week 6
Alphr AI win probability: Miami Dolphins 10.6% / Los Angeles Chargers 89.4%
- **Head to Head:** Los Angeles Chargers to win @ $1.49 (edge +22.2%) — model probability 89.4% — result: WON
- **Line / Spread:** Los Angeles Chargers -3.5 @ $1.91 (edge +0.0%) — result: LOST
- **Total (Over/Under):** Over 45.5 @ $1.91 (edge +0.0%) — result: WON
- Predicted margin: Los Angeles Chargers by 12 · Predicted total: 50
Full breakdown: https://alphr.com.au/nfl/match/2025-r6-miami-dolphins-v-los-angeles-chargers

### New Orleans Saints v New England Patriots
Mon, 13 Oct, 04:00 am AEDT · Mercedes-Benz Superdome · Week 6
Alphr AI win probability: New Orleans Saints 51.1% / New England Patriots 48.9%
- **Head to Head:** New Orleans Saints to win @ $2.60 (edge +12.6%) — model probability 51.1% — result: LOST
- **Line / Spread:** New Orleans Saints +3.5 @ $1.91 (edge +0.0%) — result: LOST
- **Total (Over/Under):** Under 46.5 @ $1.91 (edge +0.0%) — result: WON
- Predicted margin: New England Patriots by 4 · Predicted total: 44
Full breakdown: https://alphr.com.au/nfl/match/2025-r6-new-orleans-saints-v-new-england-patriots

### Pittsburgh Steelers v Cleveland Browns
Mon, 13 Oct, 04:00 am AEDT · Acrisure Stadium · Week 6
Alphr AI win probability: Pittsburgh Steelers 50.2% / Cleveland Browns 49.8%
- **Head to Head:** Pittsburgh Steelers to win @ $1.36 (edge -23.3%) — model probability 50.2% — result: WON
- **Line / Spread:** Pittsburgh Steelers -5.5 @ $1.91 (edge +0.0%) — result: WON
- **Total (Over/Under):** Over 37.5 @ $1.91 (edge +0.0%) — result: LOST
- Predicted margin: Pittsburgh Steelers by 5 · Predicted total: 40
Full breakdown: https://alphr.com.au/nfl/match/2025-r6-pittsburgh-steelers-v-cleveland-browns

### Las Vegas Raiders v Tennessee Titans
Mon, 13 Oct, 07:05 am AEDT · Allegiant Stadium · Week 6
Alphr AI win probability: Las Vegas Raiders 77.5% / Tennessee Titans 22.5%
- **Head to Head:** Las Vegas Raiders to win @ $1.54 (edge +12.6%) — model probability 77.5% — result: WON
- **Line / Spread:** Tennessee Titans +3.5 @ $1.91 (edge +0.0%) — result: LOST
- **Total (Over/Under):** Over 41.5 @ $1.91 (edge +0.0%) — result: LOST
- Predicted margin: Las Vegas Raiders by 1 · Predicted total: 46
Full breakdown: https://alphr.com.au/nfl/match/2025-r6-las-vegas-raiders-v-tennessee-titans

### Green Bay Packers v Cincinnati Bengals
Mon, 13 Oct, 07:25 am AEDT · Lambeau Field · Week 6
Alphr AI win probability: Green Bay Packers 96.8% / Cincinnati Bengals 3.2%
- **Head to Head:** Green Bay Packers to win @ $1.10 (edge +5.9%) — model probability 96.8% — result: WON
- **Line / Spread:** Green Bay Packers -14 @ $1.91 (edge +0.0%) — result: LOST
- **Total (Over/Under):** Under 44.5 @ $1.91 (edge +0.0%) — result: LOST
- Predicted margin: Green Bay Packers by 15 · Predicted total: 45
Full breakdown: https://alphr.com.au/nfl/match/2025-r6-green-bay-packers-v-cincinnati-bengals

### Tampa Bay Buccaneers v San Francisco 49ers
Mon, 13 Oct, 07:25 am AEDT · Raymond James Stadium · Week 6
Alphr AI win probability: Tampa Bay Buccaneers 51.7% / San Francisco 49ers 48.3%
- **Head to Head:** Tampa Bay Buccaneers to win @ $1.52 (edge -14.1%) — model probability 51.7% — result: WON
- **Line / Spread:** San Francisco 49ers +3.5 @ $1.91 (edge +0.0%) — result: LOST
- **Total (Over/Under):** Over 46.5 @ $1.91 (edge +0.0%) — result: WON
- Predicted margin: Tampa Bay Buccaneers by 2 · Predicted total: 52
Full breakdown: https://alphr.com.au/nfl/match/2025-r6-tampa-bay-buccaneers-v-san-francisco-49ers

### Kansas City Chiefs v Detroit Lions
Mon, 13 Oct, 11:20 am AEDT · GEHA Field at Arrowhead Stadium · Week 6
Alphr AI win probability: Kansas City Chiefs 52.5% / Detroit Lions 47.5%
- **Head to Head:** Kansas City Chiefs to win @ $1.70 (edge -6.2%) — model probability 52.5% — result: WON
- **Line / Spread:** Kansas City Chiefs -2.5 @ $1.91 (edge +0.0%) — result: WON
- **Total (Over/Under):** Over 51.5 @ $1.91 (edge +0.0%) — result: LOST
- Predicted margin: Kansas City Chiefs by 3 · Predicted total: 62
Full breakdown: https://alphr.com.au/nfl/match/2025-r6-kansas-city-chiefs-v-detroit-lions

### Atlanta Falcons v Buffalo Bills
Tue, 14 Oct, 10:15 am AEDT · Mercedes-Benz Stadium · Week 6
Alphr AI win probability: Atlanta Falcons 42.0% / Buffalo Bills 58.0%
- **Head to Head:** Buffalo Bills to win @ $1.49 (edge -9.2%) — model probability 58.0% — result: LOST
- **Line / Spread:** Atlanta Falcons +3.5 @ $1.91 (edge +0.0%) — result: WON
- **Total (Over/Under):** Over 49.5 @ $1.91 (edge +0.0%) — result: LOST
- Predicted margin: Buffalo Bills by 2 · Predicted total: 53
Full breakdown: https://alphr.com.au/nfl/match/2025-r6-atlanta-falcons-v-buffalo-bills

### Washington Commanders v Chicago Bears
Tue, 14 Oct, 11:15 am AEDT · FedExField · Week 6
Alphr AI win probability: Washington Commanders 72.5% / Chicago Bears 27.5%
- **Head to Head:** Washington Commanders to win @ $1.39 (edge +0.4%) — model probability 72.5% — result: LOST
- **Line / Spread:** Washington Commanders -5.5 @ $1.91 (edge +0.0%) — result: LOST
- **Total (Over/Under):** Under 49.5 @ $1.91 (edge +0.0%) — result: WON
- Predicted margin: Washington Commanders by 7 · Predicted total: 45
Full breakdown: https://alphr.com.au/nfl/match/2025-r6-washington-commanders-v-chicago-bears

## Model performance (2025)
_No settled predictions yet this season._

## More NFL predictions
- Previous round: https://alphr.com.au/nfl/2025/round/5 (markdown: /nfl/2025/round/5.md)
- Next round: https://alphr.com.au/nfl/2025/round/7 (markdown: /nfl/2025/round/7.md)
- All NFL rounds & tips: https://alphr.com.au/nfl (markdown: /nfl.md)

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All predictions are published before kick-off and verified after full time. Free, no login. 18+ gamble responsibly (AU).
Last updated: 2025-10-14 00:15 UTC (latest tip update)